Pure Encapsulations GI Integrity – 120 caps

$82.50

Targeted iTargeted

L-glutamine, N-acetyl-d-glucosamine, gamma oryzanol, and aloe vera extract in a practitioner-formulated blend.

Designed to support intestinal integrity and the protective mucosal lining of the gastrointestinal tract.

Only 1 left in stock

Ships same business day from Melbourne (orders before 2pm)

Combine With a Probiotic

Researched Nutritionals Corebiotic Sensitive - 60 Capsules

Corebiotic Sensitive provides three Bacillus spore-forming probiotic strains providing 11 billion CFU per dose.
Prebiotic-free formulation designed for individuals following low FODMAP diets or with sensitivities to fiber-based prebiotics.

What is Pure Encapsulations GI Integrity and who is it for?

GI Integrity is a four-ingredient formula designed to support the structure and function of your gastrointestinal lining. It combines L-glutamine (the gut’s preferred fuel source), N-acetyl-d-glucosamine (a building block for the protective mucosal layer), gamma oryzanol (traditionally used in gastric support), and a concentrated aloe vera extract standardised for polysaccharide content. This is formulated for adults aged 18 and up who want targeted nutritional support for intestinal health and the integrity of the mucosal barrier.

You might consider this if you’re dealing with ongoing digestive discomfort, have been advised by a practitioner to support your gut lining, or are managing a condition where intestinal integrity matters. It’s also useful if you’re taking steps to rebuild digestive resilience after a period of stress, dietary changes, or other factors that affect gut health. This makes sense as a foundational support rather than a quick fix—it’s designed to work over weeks, not days.

Fairfield Nutrition Thoughts

Intestinal permeability and mucosal integrity are increasingly recognised as foundational to both digestive health and broader immune function. Many people dealing with ongoing digestive discomfort, food sensitivities, or immune challenges benefit from targeted support for the gut barrier itself, not just symptom management. GI Integrity addresses this directly by providing the specific amino acids and plant compounds the intestinal lining needs to maintain its structure and function.

The evidence here is solid. L-glutamine’s role in maintaining enterocyte health and villous function is well-established in clinical literature, and the formula’s other ingredients have both traditional use and preclinical support. Aloe vera polysaccharides, in particular, have shown positive results in human trials for intestinal support. We stock this because it’s a clean, well-dosed formulation from a brand known for rigorous quality standards, and because the combination of ingredients addresses multiple aspects of mucosal health rather than relying on a single compound.

Why This Formulation / How It Works

Most single-ingredient gut support products focus on either amino acid replacement (glutamine alone) or plant compounds (aloe, slippery elm). GI Integrity combines both approaches, plus adds N-acetyl-d-glucosamine—a direct precursor to the glycosaminoglycans that make up the mucosal matrix itself. This multi-target approach makes sense because the intestinal lining isn’t maintained by one nutrient; it requires amino acids for tissue repair, polysaccharides for structural integrity, and compounds that support the immune and inflammatory environment of the gut.

The formula uses concentrated, standardised extracts rather than whole plant powders. The aloe vera is a 200:1 extract standardised to 10% polysaccharides, which means you’re getting a consistent, research-backed dose without the volume of whole plant material. Gamma oryzanol comes from rice bran and has a long history of use in gastrointestinal applications. L-glutamine is fermented from vegetables, and the N-acetyl-d-glucosamine is derived from sustainable shellfish sources. Pure Encapsulations is GMP certified and known for rigorous third-party testing, so formulation integrity matters here.

Glutamine for enterocyte fuel and tissue repair: L-glutamine is the preferred fuel source for intestinal cells and immune cells in the small intestine. It supports the structural integrity of the mucosal lining and maintains healthy villous function—the finger-like projections that absorb nutrients. When the gut is under stress (whether from dietary factors, inflammation, or other causes), glutamine becomes conditionally essential, and supplementation can help restore function.

N-acetyl-d-glucosamine for mucosal matrix: This compound is a building block of glycosaminoglycans and glycoproteins found in the gut’s protective mucosal surface. Rather than just supporting repair, it provides the raw materials the gut lining uses to maintain its structural matrix. This is particularly useful if you’re looking to actively rebuild mucosal integrity rather than just reduce inflammation.

Aloe vera polysaccharides and gamma oryzanol for immune and inflammatory support: Aloe vera’s polysaccharide-rich inner fillet supports healthy prostaglandin metabolism, immune mediator activity, and antioxidant defenses in the gut environment. Gamma oryzanol has traditional use and preclinical support for moderating gastric secretions and promoting normal gut function. Together, they create a supportive environment for the intestinal lining to heal and function optimally.

When to Consider This

This formulation makes sense if you’re:

  • Dealing with ongoing digestive discomfort and want to support the structural integrity of your gut lining, not just manage symptoms.
  • Managing a food sensitivity or inflammatory digestive condition where mucosal barrier support is part of your recovery strategy.
  • Rebuilding digestive resilience after a period of stress, dietary changes, or other factors that affect gut health.
  • Taking steps to support your immune system from the gut up, since intestinal integrity is foundational to immune function.

This is less suitable if you’re looking for immediate symptom relief (it works over weeks, not hours) or if your primary concern is microbial balance rather than structural integrity. In those cases, you might pair this with a probiotic or consider other approaches alongside it.

How to Use

Take 2 capsules twice daily, with or between meals. This gives you a total of 4 capsules per day. You can take them with food if that suits your routine, or between meals if you prefer. Most people see noticeable support after 3-4 weeks of consistent use, so plan to use this for at least a month before assessing whether it’s making a difference for you. If you’re working with a practitioner, they may adjust the dose based on your specific situation.

Ingredients

Per 2-capsule serving:

  • L-Glutamine: 1000 mg
  • N-Acetyl-d-glucosamine: 400 mg
  • Aloe vera (inner fillet) extract (200:1, standardised to 10% polysaccharides): 300 mg
  • Gamma oryzanol (from rice bran): 50 mg

Other ingredients: Hypoallergenic plant cellulose capsule, ascorbyl palmitate (antioxidant)

Allergen information: Contains shellfish (N-acetyl-d-glucosamine derived from crab and shrimp). Free from common allergens including gluten, soy, dairy, and nuts.

Common Questions

How long does it take to work?
Most people notice support after 3-4 weeks of consistent use. The intestinal lining rebuilds gradually, so this isn’t a quick-fix supplement. If you’re not noticing a difference after 6-8 weeks, it may not be the right fit for your situation, and it’s worth discussing with your practitioner.

Can I take this with other supplements?
Yes. GI Integrity works well alongside probiotics, omega-3s, and most other supplements. If you’re taking medications or have specific health conditions, check with your practitioner first, particularly if you’re on blood thinners or managing a shellfish allergy (the N-acetyl-d-glucosamine is derived from shellfish).

Is the aloe vera extract safe?
The formula uses the inner fillet of aloe (the polysaccharide-rich gel), not the latex (the yellow substance under the skin), which is the part traditionally used as a laxative. This extract has clinical support for intestinal health and is considered safe for internal use at this dose. A human clinical trial showed positive intestinal support after 4 weeks of aloe vera supplementation.

Do I need to take this forever?
Not necessarily. Many people use GI Integrity for 2-3 months to rebuild mucosal integrity, then reassess. Some continue at a maintenance dose if they’re managing an ongoing condition. Work with your practitioner to decide what makes sense for your situation.

What’s the difference between this and slippery elm or other gut-soothing herbs?
Slippery elm and similar herbs coat and soothe the gut lining. GI Integrity takes a different approach: it provides the specific amino acids and compounds your intestinal cells need to actually repair and rebuild the mucosal layer. Both can be useful, and some people use them together—soothing support alongside structural support.

Weight 0.16 kg
Dimensions 5 × 5 × 9 cm
Shipping and Returns

Standard delivery times of 1-7 business days are to be expected. Free express delivery for orders over $175. No questions asked returns and refund within 30 days.

GTIN

8.93E+11

Brand

Pure Encapsulations

Pure Encapsulations Australia

Practitioner-grade supplements designed for purity, tolerance, and consistency

Introduction

Pure Encapsulations® is a practitioner-focused supplement brand known for its emphasis on ingredient purity, formulation clarity, and predictable tolerance. At Fairfield, we stock a broad range of Pure Encapsulations products used by practitioners worldwide. These supplements are designed around a simple principle: everything you need, and nothing you don’t. They’re commonly chosen by people who:
  • are sensitive to additives or excipients
  • want straightforward, well-tolerated formulations
  • prefer supplements that can be combined thoughtfully without unnecessary complexity

What makes Pure Encapsulations different

A focus on purity and tolerance

Many supplements include fillers, colours, coatings, or processing aids that can be problematic for some people. Pure Encapsulations products are formulated to be free from:
  • gluten and common allergens
  • artificial colours, flavours, and sweeteners
  • unnecessary binders, fillers, and coatings
  • magnesium stearate and hydrogenated oils
For many people, this results in:
  • better tolerance
  • fewer unexpected reactions
  • easier long-term use
This approach is particularly helpful for those who have struggled with supplement sensitivity in the past.

How to think about using Pure Encapsulations products

Rather than relying on highly complex blends, Pure Encapsulations focuses on clean, modular building blocks. This makes it easier to:
  • start with foundations
  • introduce products gradually
  • adjust doses without overloading the system
  • combine supplements deliberately, rather than stacking blindly
We find this suits people who want clarity and control over their supplementation.

🟢 Foundational Pure Encapsulations products

Suitable for many people, including longer-term use Foundational products are typically used to support:
  • digestion and nutrient absorption
  • baseline micronutrient intake
  • general metabolic, nervous system, and immune function
These are often the first supplements people introduce, and many remain part of longer-term routines. Common foundational options include:
  • Digestive Enzymes Ultra – broad-spectrum enzyme support to assist digestion
  • Magnesium Glycinate – gentle, well-tolerated magnesium support
  • B Complex Plus – foundational B-vitamin support without unnecessary additives
  • Zinc – essential mineral support for immune and metabolic health
  • O.N.E.™ Multivitamin – comprehensive daily micronutrient coverage
  • O.N.E.™ Omega – omega-3 fatty acids for general inflammatory balance
  • Vitamin D – foundational vitamin D support, particularly when sun exposure is limited
These products suit most people. Those with very sensitive systems may still benefit from slower introduction or lower starting doses.

🟡 Targeted Pure Encapsulations products

Best used for specific needs or time-limited support In addition to foundational products, Pure Encapsulations also offers more targeted formulations designed for particular physiological needs or life stages. These products are typically used when there is a clearer reason for doing so, and are often:
  • layered on top of foundations
  • used for defined periods rather than indefinitely
  • reassessed based on response
Targeted products may support areas such as:
  • stress and nervous system regulation
  • sleep quality
  • hormone metabolism
  • immune modulation
  • gut integrity or targeted digestive support
If you’re unsure whether a targeted product is appropriate, it’s usually better to begin with foundational support first.

A practical note on “doing more”

Because Pure Encapsulations products are generally easy to tolerate, it can be tempting to introduce several at once. In practice, starting with fewer products tends to lead to:
  • clearer feedback from your body
  • fewer unnecessary overlaps
  • greater confidence in what’s actually helping
More supplements isn’t always better — clearer thinking usually is.

Why buy Pure Encapsulations from Fairfield

  • Australian-based, stocked locally — dispatched from Melbourne
  • Fast shipping on in-stock items (same-day dispatch when ordered before 2pm)
  • Broad Pure Encapsulations range available
  • Clear, conservative guidance — we prioritise understanding over upselling
Our role isn’t just to supply supplements, but to help people use them with intention and confidence.

Pure Encapsulations products available at Fairfield

Browse the Pure Encapsulations products we stock below. If you’re new to the brand, many people begin with foundational support before layering in more targeted options as needed.
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Sale!
Original price was: $180.40.Current price is: $171.20.
Bottle of Pure Encapsulations G.I. Integrity dietary supplement with 120 gluten-free and non-GMO capsules.
Pure Encapsulations GI Integrity – 120 caps

Only 1 left in stock

Ships same business day from Melbourne (orders before 2pm)

Combine With a Probiotic

Researched Nutritionals Corebiotic Sensitive - 60 Capsules

Corebiotic Sensitive provides three Bacillus spore-forming probiotic strains providing 11 billion CFU per dose.
Prebiotic-free formulation designed for individuals following low FODMAP diets or with sensitivities to fiber-based prebiotics.