What is O.N.E. Multivitamin and who is it for?
O.N.E. Multivitamin is a once-daily formulation containing bioavailable forms of essential vitamins and minerals in a single capsule. Rather than megadoses, this formula uses activated and chelated nutrient forms selected for their absorption characteristics — including Metafolin® L-5-MTHF, vitamin D3, mixed tocopherols, and chelated trace minerals.
This product suits adults who prefer a single, well-formulated multivitamin over managing multiple bottles. It is manufactured by Pure Encapsulations, a practitioner-trusted brand known for hypoallergenic formulations free from gluten, wheat, soy, dairy, eggs, tree nuts, peanuts, sesame, GMOs, artificial colours, sweeteners, and unnecessary fillers.
Fairfield Nutrition Thoughts
Many people approach multivitamins with justified scepticism. Most commercial options are formulated around what’s cheap to include, not what your body can actually absorb or use. O.N.E. Multivitamin addresses this by using chelated minerals (bound to amino acids for better absorption), pre-methylated folate (Metafolin), and bioavailable vitamin forms rather than cheap synthetic alternatives. For someone wanting foundational micronutrient support without overthinking it, this removes a decision point.
Why This Formulation / How It Works
What makes O.N.E. different is its focus on bioavailability and form selection rather than dose magnitude. Most multivitamins use cheap synthetic forms (like cyanocobalamin instead of methylcobalamin, or folic acid instead of folate). This formula uses chelated minerals, which means they’re bound to amino acids so your digestive system can actually absorb them efficiently. It includes Metafolin, the naturally occurring form of folate that your body uses directly without requiring enzymatic conversion, which matters if you have MTHFR polymorphisms or simply want a more efficient form. The sustained-release CoQ10 (MicroActive Q10) is water-soluble, so it doesn’t sit in your digestive tract waiting to be absorbed like standard CoQ10 often does.
When to Consider This
This makes sense if you’re:
- Looking for foundational micronutrient support without managing a supplement stack
- Concerned about bioavailability and want forms your body can actually absorb efficiently
- Wanting to support normal eye health, cognitive function, and cellular energy production
- Preferring clean formulation without unnecessary additives, binders, or common allergens
⚠️ Not suitable for: Pregnant or breastfeeding women (different micronutrient needs), individuals with haemochromatosis or iron overload conditions, those taking blood thinners (vitamin K content), or anyone under 18 without healthcare provider guidance.
How to Use
Take 1 capsule daily with a meal. The food helps with absorption of fat-soluble vitamins (A, D, E) and ensures the formula moves through your digestive system at a pace that allows proper nutrient absorption. If you’re taking other supplements or medications, space them at least 2 hours apart to avoid interactions, particularly if you’re taking thyroid medication or certain antibiotics.
This is a once-daily formula, so consistency matters more than precise timing. If you forget a dose, just take your next dose the following day at your regular time. Don’t double up to make up for a missed dose.
Ingredients
Per 1 capsule serving:
Vitamin A (as retinyl palmitate) 1,500 mcg RAE
Vitamin C (as ascorbic acid) 120 mg
Vitamin D3 (as cholecalciferol) 25 mcg (1,000 IU)
Vitamin E (as d-alpha tocopheryl succinate) 15 mg AT
Vitamin K (as phylloquinone) 60 mcg
Thiamine (as thiamine HCl) 3 mg
Riboflavin 3.4 mg
Niacin (as niacinamide) 20 mg
Vitamin B6 (as pyridoxal 5-phosphate) 4 mg
Folate (as Metafolin L-5-methyltetrahydrofolate) 400 mcg DFE
Vitamin B12 (as methylcobalamin) 8 mcg
Biotin 300 mcg
Pantothenic acid (as calcium d-pantothenate) 10 mg
Calcium (as calcium citrate malate) 100 mg
Iodine (as potassium iodide) 150 mcg
Magnesium (as magnesium citrate) 50 mg
Zinc (as zinc citrate) 6 mg
Selenium (as selenium methionine) 55 mcg
Copper (as copper citrate) 0.5 mg
Manganese (as manganese citrate) 1 mg
Chromium (as chromium polynicotinate) 50 mcg
Molybdenum (as molybdenum glycinate chelate) 25 mcg
Choline (as choline bitartrate) 25 mg
Inositol 25 mg
Lutein 6 mg
Zeaxanthin 1.2 mg
Lycopene 3 mg
Alpha lipoic acid 25 mg
Coenzyme Q10 (as ubiquinone and MicroActive Q10) 30 mg
Other ingredients: Hypromellose (vegetarian capsule), microcrystalline cellulose, ascorbyl palmitate, mixed tocopherols
Allergen information: Free from wheat, soy, dairy, eggs, tree nuts, peanuts, sesame, gluten, artificial colours, artificial sweeteners, GMOs, magnesium stearate, and unnecessary binders or fillers.
Common Questions
Is this enough, or should I take additional supplements?
This provides foundational micronutrient support. Whether you need additional supplements depends on your individual situation: your diet quality, any specific health concerns, and what your healthcare practitioner recommends. Some people use this as their baseline and add targeted support (like omega-3s or specific herbs) based on their needs. Others find this sufficient. The point is that O.N.E. handles the micronutrient essentials so you can make more intentional decisions about what else you actually need.
Why does this include CoQ10?
CoQ10 supports mitochondrial energy production and acts as an antioxidant, making it relevant to overall cellular health rather than treating any specific condition. The inclusion of both standard and sustained-release forms is practical: standard CoQ10 provides immediate availability, while the water-soluble sustained-release form ensures absorption even if your digestion is sluggish.
Can I take this if I’m on blood thinners?
The vitamin K content (60 mcg) is relatively modest, but you should discuss any multivitamin with your prescribing doctor if you’re on warfarin or similar medications, as vitamin K can interact with these drugs. Other blood thinners typically have fewer interactions with vitamin K, but it’s worth confirming with your healthcare provider.
Why is the folate in this form, and does it matter?
This uses Metafolin (L-5-methyltetrahydrofolate), the naturally occurring form of folate that your body uses directly. Standard multivitamins use folic acid, a synthetic form that requires enzymatic conversion. If you have MTHFR polymorphisms or simply want a more efficient form, this matters. If you don’t have genetic variations affecting folate metabolism, both forms work, but the Metafolin form is more universally available to your cells.
Warnings & Storage
Do not use if: Pregnant or breastfeeding (different micronutrient requirements apply), under 18 without healthcare provider guidance, or you have haemochromatosis or iron overload conditions.
Cautions: If you're taking blood thinners (warfarin), discuss vitamin K content with your prescribing doctor. If you're taking thyroid medication, space this supplement at least 4 hours apart from your medication. If you have a history of kidney disease or are taking medications that affect mineral metabolism, consult your healthcare provider before use.
Storage: Store in a cool, dry place away from direct sunlight. Keep out of reach of children. No refrigeration required.
Always consult your healthcare professional before use if you have any pre-existing conditions or are taking medications.



















