What is O.N.E. Multivitamin and who is it for?
O.N.E. Multivitamin is a once-daily formulation containing essential vitamins and minerals in a single capsule. This formula uses activated and chelated nutrient forms — including Metafolin® L-5-MTHF, vitamin D3, mixed tocopherols, and chelated trace minerals — rather than standard synthetic alternatives.
This product suits adults who prefer a single, well-formulated multivitamin over managing multiple bottles. It is manufactured by Pure Encapsulations, a practitioner-grade brand known for hypoallergenic formulations free from gluten, wheat, soy, dairy, eggs, tree nuts, peanuts, sesame, GMOs, artificial colours, sweeteners, and unnecessary fillers.
Fairfield Nutrition Thoughts
O.N.E. Multivitamin uses chelated minerals (bound to amino acids), pre-methylated folate (Metafolin®), and selected vitamin forms rather than common synthetic alternatives such as cyanocobalamin or folic acid. For someone wanting a considered daily micronutrient formula in a single capsule — without managing multiple products — this is a straightforward option from a practitioner-grade manufacturer.
Why This Formulation / How It Works
What distinguishes O.N.E. is its focus on nutrient form selection rather than dose magnitude. Most multivitamins use common synthetic forms — cyanocobalamin instead of methylcobalamin, folic acid instead of methylfolate. This formula uses chelated minerals, meaning they are bound to amino acids, a form widely used in practitioner-grade formulations. It includes Metafolin®, the naturally occurring form of folate, rather than synthetic folic acid. The sustained-release CoQ10 (MicroActive® Q10) uses a water-soluble delivery format, distinct from standard fat-soluble CoQ10 preparations. Mixed tocopherols provide vitamin E as a spectrum rather than isolated alpha-tocopherol.
When to Consider This
This product may suit you if you:
- Prefer a single daily capsule over managing multiple individual supplements
- Value chelated and methylated nutrient forms over standard synthetic forms
- Want a formula that includes CoQ10, lutein, zeaxanthin, lycopene, and alpha lipoic acid alongside core vitamins and minerals
- Prefer a hypoallergenic formulation free from gluten, dairy, soy, and common additives
Always consult a qualified healthcare practitioner before use, particularly if you are taking medication or have specific dietary requirements.
How to Use
Take 1 capsule daily with a meal. The food helps with absorption of fat-soluble vitamins (A, D, E) and ensures the formula moves through your digestive system at a pace that allows proper nutrient absorption. If you’re taking other supplements or medications, space them at least 2 hours apart to avoid interactions, particularly if you’re taking thyroid medication or certain antibiotics.
This is a once-daily formula, so consistency matters more than precise timing. If you forget a dose, just take your next dose the following day at your regular time. Don’t double up to make up for a missed dose.
Ingredients
Per 1 capsule serving:
Vitamin A (as retinyl palmitate) 1,500 mcg RAE
Vitamin C (as ascorbic acid) 120 mg
Vitamin D3 (as cholecalciferol) 25 mcg (1,000 IU)
Vitamin E (as d-alpha tocopheryl succinate) 15 mg AT
Vitamin K (as phylloquinone) 60 mcg
Thiamine (as thiamine HCl) 3 mg
Riboflavin 3.4 mg
Niacin (as niacinamide) 20 mg
Vitamin B6 (as pyridoxal 5-phosphate) 4 mg
Folate (as Metafolin L-5-methyltetrahydrofolate) 400 mcg DFE
Vitamin B12 (as methylcobalamin) 8 mcg
Biotin 300 mcg
Pantothenic acid (as calcium d-pantothenate) 10 mg
Calcium (as calcium citrate malate) 100 mg
Iodine (as potassium iodide) 150 mcg
Magnesium (as magnesium citrate) 50 mg
Zinc (as zinc citrate) 6 mg
Selenium (as selenium methionine) 55 mcg
Copper (as copper citrate) 0.5 mg
Manganese (as manganese citrate) 1 mg
Chromium (as chromium polynicotinate) 50 mcg
Molybdenum (as molybdenum glycinate chelate) 25 mcg
Choline (as choline bitartrate) 25 mg
Inositol 25 mg
Lutein 6 mg
Zeaxanthin 1.2 mg
Lycopene 3 mg
Alpha lipoic acid 25 mg
Coenzyme Q10 (as ubiquinone and MicroActive Q10) 30 mg
Other ingredients: Hypromellose (vegetarian capsule), microcrystalline cellulose, ascorbyl palmitate, mixed tocopherols
Allergen information: Free from wheat, soy, dairy, eggs, tree nuts, peanuts, sesame, gluten, artificial colours, artificial sweeteners, GMOs, magnesium stearate, and unnecessary binders or fillers.
Common Questions
Is this enough, or should I take additional supplements?
This provides foundational micronutrient support. Whether you need additional supplements depends on your individual situation: your diet quality, any specific health concerns, and what your healthcare practitioner recommends. Some people use this as their baseline and add targeted support (like omega-3s or specific herbs) based on their needs. Others find this sufficient. The point is that O.N.E. handles the micronutrient essentials so you can make more intentional decisions about what else you actually need.
Why does this include CoQ10?
CoQ10 supports mitochondrial energy production and acts as an antioxidant, making it relevant to overall cellular health rather than treating any specific condition. The inclusion of both standard and sustained-release forms is practical: standard CoQ10 provides immediate availability, while the water-soluble sustained-release form ensures absorption even if your digestion is sluggish.
Can I take this if I’m on blood thinners?
The vitamin K content (60 mcg) is relatively modest, but you should discuss any multivitamin with your prescribing doctor if you’re on warfarin or similar medications, as vitamin K can interact with these drugs. Other blood thinners typically have fewer interactions with vitamin K, but it’s worth confirming with your healthcare provider.
Why is the folate in this form, and does it matter?
This uses Metafolin (L-5-methyltetrahydrofolate), the naturally occurring form of folate that your body uses directly. Standard multivitamins use folic acid, a synthetic form that requires enzymatic conversion. If you have MTHFR polymorphisms or simply want a more efficient form, this matters. If you don’t have genetic variations affecting folate metabolism, both forms work, but the Metafolin form is more universally available to your cells.
Warnings & Storage
Do not use if: Pregnant or breastfeeding (different micronutrient requirements apply), under 18 without healthcare provider guidance, or you have haemochromatosis or iron overload conditions.
Cautions: If you're taking blood thinners (warfarin), discuss vitamin K content with your prescribing doctor. If you're taking thyroid medication, space this supplement at least 4 hours apart from your medication. If you have a history of kidney disease or are taking medications that affect mineral metabolism, consult your healthcare provider before use.
Storage: Store in a cool, dry place away from direct sunlight. Keep out of reach of children. No refrigeration required.
Always consult your healthcare professional before use if you have any pre-existing conditions or are taking medications.

















