Researched Nutritionals RenewGut+ 120 Capsules

What is Researched Nutritionals RenewGut+ and who is it for?

RenewGut+ is a comprehensive gut-lining support formula designed for individuals seeking to strengthen their digestive barrier and create an optimal environment for beneficial bacteria. It combines hydrolyzed collagen peptides, targeted botanicals, and key micronutrients in a single formula that works synergistically to support intestinal integrity, mucus layer health, and normal digestive function. This product is particularly valuable for anyone working with a practitioner to address digestive challenges, those transitioning their diet, or individuals using probiotics who want to ensure their gut environment is properly nourished.

RenewGut+ is designed to be used alongside a quality probiotic like CoreBiotic® or Multi-Biome™—think of it as preparing the soil before planting seeds. The probiotic introduces beneficial strains, while RenewGut+ creates the conditions for those strains to thrive.

Why choose this multi-mechanism approach?

The digestive barrier isn’t a single structure—it’s a complex ecosystem involving tight junction proteins, a protective mucus layer, immune signalling molecules (cytokines), and microbial metabolites. Addressing only one of these components is like fixing one pillar of a building while ignoring the others. Renew Gut’s formulation recognizes this complexity.

Many practitioners recommend simple collagen or L-glutamine for gut support, but RenewGut+ goes further. It includes hydrolyzed collagen peptides (which provide the amino acid building blocks for tight junction repair), N-acetyl-D-glucosamine (which directly supports the mucin layer that protects the intestinal lining), and targeted botanicals that modulate the immune and histamine responses within the digestive tract itself. This layered approach means you’re not just feeding the gut—you’re actively supporting its structural and functional recovery.

How does it work?

Imagine your digestive lining as a selective barrier—it should allow beneficial nutrients through while keeping harmful substances out. When this barrier becomes compromised (a state practitioners call “increased intestinal permeability”), undigested food particles and microbial metabolites can cross into the bloodstream, triggering systemic inflammation. RenewGut+ works on multiple levels to restore this barrier’s integrity and function.

Structural Support—Collagen and Amino Acids: Hydrolyzed collagen peptides (Types I and III) are broken down into absorbable amino acids, particularly glycine, proline, and hydroxyproline. These amino acids are the literal building blocks of the intestinal lining’s structural proteins. They directly nourish enterocytes (the cells lining your gut) and provide the substrate needed to repair and strengthen tight junctions—the protein complexes that control what passes through the intestinal barrier.

Mucus Layer Enhancement—NAG and GutGard®: The mucus layer is your gut’s first line of defense. N-acetyl-D-glucosamine (NAG) is a precursor to glycosaminoglycans, which are essential components of the mucin that forms this protective layer. GutGard® is a patented, high-potency form of deglycyrrhized licorice (DGL) that acts as a demulcent—it soothes and protects the intestinal lining while promoting healthy mucin production. The patented form means you get therapeutic benefit at a lower dose with minimal glycyrrhizin (the compound that can affect electrolyte balance with long-term use).

Immune Modulation—Luteolin and Zinc Carnosine: Luteolin is a bioflavonoid that reduces mast cell degranulation—the process by which mast cells release histamine and inflammatory mediators in response to triggers. Zinc carnosine is a chelated form of zinc that has dual action: it fortifies tight junctions at the molecular level and supports normal immune signalling. Together, these ingredients help calm the gut’s over-reactive immune response while maintaining appropriate immune vigilance.

Histamine and Cytokine Balance—Black Cumin and Comprehensive Support: Black cumin (Nigella sativa) provides antihistamine support specifically within the digestive tract, helping to manage the histamine that contributes to digestive distress. The formula as a whole promotes healthy cytokine activity—the chemical messengers that coordinate immune and inflammatory responses—creating an environment where the gut can heal rather than remain in a state of chronic irritation.

What can this support?

This formula provides nutritional support for:

Digestive Sensitivity: Individuals experiencing occasional digestive discomfort, bloating, or irregular transit may benefit from RenewGut+’s multi-mechanism support for barrier integrity and immune modulation within the gut.

Post-Antibiotic Recovery: Antibiotics can damage the gut lining and disrupt the microbial community. RenewGut+ provides the nutritional substrates needed to restore barrier function while a quality probiotic rebuilds microbial diversity.

Food Sensitivity Management: Those managing food sensitivities often have compromised barrier function. By strengthening tight junctions and supporting the mucus layer, RenewGut+ may help reduce the translocation of food antigens across the intestinal barrier.

Probiotic Optimization: Probiotics work best in a healthy gut environment. Using RenewGut+ alongside a probiotic ensures the microbiome has both the beneficial strains and the nutritional support needed to establish and thrive.

Histamine Sensitivity: Individuals managing histamine sensitivity often benefit from targeted support for histamine metabolism within the gut itself. RenewGut+’s combination of luteolin, black cumin, and zinc carnosine addresses this specific need.

Nutrient Absorption Optimization: A healthy, intact gut barrier is essential for optimal nutrient absorption. By supporting barrier function, RenewGut+ helps ensure that the nutrients from your diet and other supplements are properly absorbed.

Common questions

How long does it take to see results?
Gut barrier repair is a gradual process. Most practitioners recommend using RenewGut+ for at least 8-12 weeks to allow for meaningful restoration of intestinal integrity. Some individuals notice improvements in digestive comfort within 2-3 weeks, while others require longer support. Consistency and use alongside a supportive diet are key.

Can I use this with probiotics?
Yes—in fact, this is the ideal approach. RenewGut+ is specifically formulated to work alongside a quality probiotic. The probiotic introduces beneficial strains, while RenewGut+ creates the nutritional and structural environment where those strains can establish and flourish. Many practitioners recommend using them together.

Is this suitable for long-term use?
Yes. RenewGut+ is formulated without ingredients like aloe vera (not recommended for long-term use) or L-glutamine (which can elevate glutamate levels). The formula uses hydrolyzed collagen peptides and a patented form of DGL with lower glycyrrhizin content, making it appropriate for extended use under practitioner guidance.

What’s the difference between this and simple collagen supplements?
While collagen provides amino acids for structural support, RenewGut+ is a comprehensive formula that addresses multiple aspects of gut health: structural repair (collagen), mucus layer support (NAG and GutGard®), immune modulation (luteolin, zinc carnosine), and histamine management (black cumin). It’s a complete system rather than a single-nutrient approach.

Can I take this if I have a sensitive stomach?
RenewGut+ is well-tolerated by most individuals. However, if you have extreme digestive sensitivity, it’s worth starting with a lower dose (2 capsules instead of 4) and gradually increasing. The formula’s ingredients are specifically chosen to support and calm the digestive tract rather than irritate it. Consult your practitioner if you have concerns.

Does this contain any allergens?
RenewGut+ is manufactured without milk, eggs, fish, tree nuts, peanuts, sesame, wheat, soy, and gluten. It is produced in a facility that may process other ingredients containing these allergens. The gelatin capsule is the only animal-derived ingredient, so it is not suitable for vegans.

Key Features

• Hydrolyzed collagen peptides (Types I and III) for structural intestinal support
• GutGard® patented deglycyrrhized licorice for enhanced mucus layer health
• N-Acetyl-D-glucosamine for tight junction integrity
• Zinc carnosine for dual-action barrier and immune support
• Luteolin and black cumin for histamine and mast cell modulation
• Clean formula: no artificial additives, colours, or unnecessary fillers
• Designed to work synergistically with quality probiotics

Suggested Use

As a dietary supplement, take 4 capsules once daily or as directed by your healthcare professional. For optimal results, use consistently for at least 8-12 weeks. RenewGut+ is designed to work alongside a quality probiotic such as CoreBiotic® or Multi-Biome™. If pregnant or nursing, consult your healthcare professional before use.

Ingredients (per serving of 4 capsules)

• RenewGut+™ Blend (1900 mg) – Hydrolyzed collagen peptides (Type I & III), N-Acetyl D-glucosamine, GutGard® deglycyrrhized licorice, Black Cumin (Nigella sativa) seed, Zinc Carnosine, Luteolin
• Zinc (from Zinc Carnosine) – 15 mg

Other Ingredients: Gelatin (capsule)
Allergen Information: Manufactured without milk, eggs, fish, tree nuts, peanuts, sesame, wheat, soy, and gluten. Produced in a facility that may process other ingredients containing these allergens.
Not suitable for vegans.

These statements have not been evaluated by the TGA. This product is not intended to diagnose, treat, cure, or prevent any disease.