MyBrainCo 100g Pure TMG
$29.80
Methylation supplement: Trimethylglycine (TMG), also known as Betaine Anhydrous, in pure powder form.
MyBrainCo pharmaceutical-grade TMG with lab-tested purity certification. Powder form dissolves readily in water or liquid for flexible daily dosing.
In stock
Ships same business day from Melbourne (orders before 2pm)
What is MyBrainCo Pure TMG and who is it for?
MyBrainCo Pure TMG is a single-ingredient trimethylglycine powder providing 1 g of pharmaceutical-grade Betaine Anhydrous per serve. TMG is a naturally occurring compound found in beetroot, spinach, and whole grains, and it serves as a methyl donor in the body’s methylation cycle. This product is designed for people who are actively working on methylation support, particularly those using NAD+ precursors, high-dose B vitamins, or other protocols with significant methyl demand.
You might consider this if you’re working with a practitioner on a methylation protocol and want a simple, unflavoured powder you can add to an existing drink routine. Because it’s a single ingredient with no fillers or excipients, it’s also a practical option for people who want precise control over their TMG dose or who are sensitive to capsule binders and coatings.
Fairfield Nutrition Thoughts
TMG comes up most often in practice when someone is already using NMN, NR, or high-dose B vitamins and their practitioner is thinking about methyl donor balance. These protocols can draw heavily on the methylation cycle, and TMG is one of the more direct ways to provide additional methyl groups without adding complexity to a protocol.
Why This Formulation / How It Works
Most TMG products come in capsule form, which limits flexibility around dosing and adds excipients some people prefer to avoid. This product is pure Betaine Anhydrous powder with nothing else added, giving you full control over dose and easy integration into a morning drink, protein shake, or other liquid. The pharmaceutical-grade specification and lab-testing documentation are relevant here because TMG purity varies considerably across bulk powder suppliers.
Role in the Methylation Cycle
TMG donates one of its three methyl groups in the remethylation of homocysteine to methionine, a reaction catalysed by the enzyme betaine-homocysteine methyltransferase (BHMT). This is one of two pathways the body uses to recycle homocysteine, the other being the folate and B12-dependent route. Having both pathways available is relevant when one is under strain, such as during high methylation demand from NAD+ precursor supplementation or when B12 and folate status is suboptimal.
Osmoprotective Role in Cells
Beyond its methyl donor function, TMG acts as an osmolyte, meaning it helps cells regulate volume and maintain structural integrity under osmotic stress. It concentrates in tissues with high metabolic activity and is involved in protecting proteins and cell membranes when cells are under physiological stress. This role is distinct from its methylation function and is part of why TMG is found naturally in plant foods that experience environmental stress.
When to Consider This
This targeted methylation supplement makes sense if you’re:
- Using NAD+ precursors such as NMN or NR and your practitioner has recommended adding methyl donor support to the protocol.
- On a high-dose B vitamin protocol where additional methylation support has been identified as relevant.
- Working with a practitioner who has identified elevated homocysteine as something to address through nutritional means.
- Looking for a pure, additive-free TMG source you can add to an existing drink without capsules or fillers.
Supplement strategy: TMG is most commonly introduced once a foundational B-vitamin and methylation protocol is already in place, often as a complement to methylated B12 and folate rather than a standalone approach. Many people add it when beginning NAD+ precursor supplementation, as a way of providing additional methyl groups to support the increased demand those protocols can place on the methylation cycle.
⚠️ Not suitable for: Children under 15 years, pregnant or breastfeeding women, people taking prescription medications without prior medical consultation.
How to Use
The serving size is 1 g (approximately one small scoop), blended into 150-200 mL of water, juice, protein shake, or any liquid of your choice. Each 100 g bag provides 100 serves. The manufacturer recommends daily use for consistent effect.
Always use a dry spoon when measuring, reseal the bag after each use, and consume within 150 days of opening. Store below 25°C in a cool, dry place away from direct sunlight.
Ingredients
Per 1 g serving:
Trimethylglycine (Betaine Anhydrous) 1 g
No other ingredients. Pure pharmaceutical-grade powder with no excipients, fillers, or flow agents.
Allergen information: Free from gluten, dairy, and GMO ingredients. Suitable for vegans.
Common Questions
How is TMG different from betaine HCl?
They’re different compounds despite sharing the “betaine” name. TMG (Betaine Anhydrous) is the methyl donor form used in methylation pathways. Betaine HCl is used as a digestive acid supplement and has a different application entirely. This product is TMG, not betaine HCl.
Do I need TMG if I’m already taking methylated B vitamins?
Methylated B vitamins (B12 and folate) support the folate-dependent remethylation pathway. TMG supports a separate, parallel pathway. Many practitioners use both, particularly when someone is on NAD+ precursor supplementation or has high methylation demands. Whether you need both depends on your individual protocol and is worth discussing with your practitioner.
Can I take more than 1 g per day?
The manufacturer’s serving size is 1 g daily. Some practitioners use higher amounts in specific protocols, but this should be guided by a healthcare professional familiar with your situation. Stick to the label recommendation unless directed otherwise.
Does TMG powder have a taste?
TMG has a mildly sweet taste, which most people find neutral or unnoticeable when mixed into a drink. It dissolves readily in water and doesn’t significantly alter the flavour of protein shakes or juice.
Warnings & Storage
Do not use if: You are pregnant or breastfeeding, under 15 years of age, or have been advised to avoid methyl donors by your healthcare provider.
Cautions: Consult your healthcare professional before use if you are taking any prescription medications, have a pre-existing medical condition, or are planning surgery. Not a sole source of nutrition.
Storage: Store below 25°C in a cool, dry place away from direct sunlight and heat. Always use a dry spoon. Reseal after each use. Consume within 150 days of opening.
Always consult your healthcare professional before use if you have any pre-existing conditions or are taking medications.
| Weight | 0.19 kg |
|---|---|
| Dimensions | 6 × 6 × 10 cm |
| GTIN | 9.35E+12 |
