Seeking Health Hydroxo B12 with Folinic Acid
$37.50
B-vitamin supplement: Hydroxocobalamin (B12) and folinic acid (B9) in methyl-free forms. Seeking Health lozenge formulation designed for those sensitive to methylated nutrients. Non-methylated forms that convert to active methylated B vitamins in your body as needed.
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What is Hydroxo B12 with Folinic Acid and who is it for?
Hydroxo B12 with Folinic Acid combines two essential B vitamins in their non-methylated forms: hydroxocobalamin (B12) and folinic acid (folate/B9). This lozenge is designed for people who experience sensitivity to methylated nutrients like methylcobalamin or methylfolate, which can cause nervousness, rapid heartbeat, or other unwanted reactions. The formula provides potent doses of both vitamins in a form your body readily converts to active methylated versions as needed, making it ideal for methylation support without the side effects some people experience with pre-methylated supplements.
This product makes sense if you’re building a methylation-support protocol, managing MTHFR-related considerations, or have discovered that methylated B vitamins don’t work well for you. The lozenge delivery method supports absorption without requiring swallowing pills, and the formula is suitable across a wide age range, including during pregnancy and breastfeeding when B vitamin needs increase.
Fairfield Nutrition Thoughts
Many people discover they’re sensitive to methylated B vitamins only after experiencing side effects like anxiety, rapid heartbeat, or insomnia. Standard methylated B12 and folate supplements can be problematic for these individuals, yet B vitamin support remains essential for methylation pathways, energy production, and neurological function. This product fills that gap by providing the precursor forms that your body converts to methylated versions on demand, avoiding the sudden methylation load that triggers reactions in sensitive people.
The evidence for B12 and folate roles in methylation, energy metabolism, and homocysteine regulation is well-established. Hydroxocobalamin specifically has been used clinically for decades and converts efficiently to both adenosylcobalamin and methylcobalamin in tissues. Folinic acid (unlike folic acid) bypasses the MTHFR enzyme entirely, making it accessible even for people with MTHFR variations.
Why This Formulation / How It Works
Most B-complex supplements use either synthetic folic acid (which requires multiple enzyme conversions) or pre-methylated forms like methylcobalamin and methylfolate. This product takes a different approach by using hydroxocobalamin and folinic acid—the intermediate forms that sit between synthetic and fully methylated. For people sensitive to methylated nutrients, this distinction matters enormously. You get the B vitamin support your body needs without the sudden methylation surge that triggers reactions.
The lozenge delivery is more than convenience. Dissolving under the tongue allows direct absorption through oral mucosa, bypassing some digestive processes and supporting faster utilization. This form is particularly valuable for people with compromised digestion, bariatric surgery history, or absorption challenges.
How B12 and Folate Work Together in Methylation
Hydroxocobalamin and folinic acid function as cofactors in methylation pathways, where they facilitate the transfer of methyl groups needed for DNA synthesis, neurotransmitter production, immune function, and cellular repair. B12 specifically helps regenerate tetrahydrofolate, the active form of folate that participates in these reactions. When either nutrient is insufficient, methylation slows and homocysteine accumulates—a marker associated with cardiovascular and neurological concerns. By providing both nutrients in accessible forms, this formula supports the complete methylation cycle.
Conversion to Active Forms
Hydroxocobalamin converts in your tissues to adenosylcobalamin (the form used in mitochondrial energy pathways) and methylcobalamin (used in methylation reactions). Folinic acid converts to methylfolate through a single enzyme step, making it efficient even for people with MTHFR variations. This on-demand conversion allows your body to regulate methylation intensity, preventing the overmethylation reactions that sensitive individuals experience with pre-methylated supplements.
When to Consider This
This formulation provides support for methylation pathways and B vitamin needs. It makes sense if you’re:
Scenario 1: You’ve tried methylated B vitamins and experienced side effects like anxiety, insomnia, rapid heartbeat, or headaches, but still need B12 and folate support.
Scenario 2: You have MTHFR variations and want to support methylation without the intensity of pre-methylated supplements.
Scenario 3: You’re in a life stage (pregnancy, breastfeeding, or recovery from illness) where B vitamin needs are elevated and you want a gentle, accessible form.
Supplement strategy: Many people introduce this as part of a broader methylation-support protocol, often alongside other foundational nutrients like B6 and choline. It’s commonly used for several months as part of addressing homocysteine levels or supporting energy and cognitive function. This product provides B12 and folate only; if you want additional methyl-free B vitamins, Seeking Health’s B Minus pairs well with it.
⚠️ Not suitable for: Children under 4 years old, individuals with B12 or folate sensitivities, those taking certain medications that interact with B vitamins (consult your healthcare provider)
How to Use
Dosage: Take 1 lozenge daily as needed, or as directed by your healthcare professional. Each lozenge provides 1,000 mcg of hydroxocobalamin and 1,360 mcg DFE (800 mcg) of folinic acid. The lozenge can be broken into smaller pieces if you prefer a lower dose.
Timing: Do not take within 5 hours of bedtime, as B vitamins can interfere with sleep for some people. Morning or early afternoon dosing works best for most users.
Delivery method: Dissolve the lozenge under your tongue or allow it to dissolve slowly in your mouth. This supports absorption and makes it easy for children or anyone with difficulty swallowing pills.
Ingredients
Per lozenge:
Hydroxocobalamin (Vitamin B12): 1,000 mcg
Folinic Acid (Methyl-free Folate): 800 mcg (1,360 mcg DFE)
Other ingredients: Xylitol, natural berry flavor, cellulose, stearic acid, magnesium stearate
Allergen information: Free from common allergens. Suitable for vegetarian and vegan diets.
Common Questions
What’s the difference between this and methylated B vitamins?
This product uses hydroxocobalamin and folinic acid, which your body converts to methylated forms (methylcobalamin and methylfolate) as needed. People sensitive to pre-methylated supplements experience fewer side effects with this approach because the conversion happens gradually in tissues rather than all at once. If you’ve had reactions to methylated B vitamins, this is worth trying.
Can I take this if I have MTHFR mutations?
Yes. Folinic acid bypasses the MTHFR enzyme entirely, converting to methylfolate through a different pathway. This makes it accessible for people with MTHFR variations who struggle with folic acid or methylfolate. Hydroxocobalamin also works well for MTHFR-related protocols.
When should I take this, and can I take it with food?
Take it in the morning or early afternoon—avoid the 5 hours before bedtime as B vitamins can be stimulating. You can take it with or without food. If you’re using it as a lozenge, dissolving it under your tongue bypasses some digestive processes and may support faster absorption.
Is this suitable during pregnancy and breastfeeding?
Yes. Seeking Health specifically notes this formulation is suitable for pregnancy and breastfeeding. B12 and folate are especially important during these life stages for fetal development and milk production. If you’re pregnant or breastfeeding, confirm with your healthcare provider that this dosage aligns with your individual needs.
Can I break the lozenge into smaller doses?
Yes. The lozenge can be broken into smaller pieces if you want to take a lower dose or give it to children. Many parents of children with MTHFR variations use this approach.
Warnings & Storage
Do not use if: You have a known sensitivity or allergy to B vitamins, are taking medications that interact with B vitamins, or are under 4 years old without healthcare provider guidance.
Cautions: B vitamins can be stimulating for some people; avoid taking within 5 hours of bedtime. If you experience any adverse reactions, discontinue use and consult your healthcare provider. This product is not suitable for people with pernicious anemia unless under medical supervision.
Storage: Keep the container closed in a cool, dry place away from direct sunlight and out of reach of children.
Always consult your healthcare professional before use if you have any pre-existing conditions or are taking medications.
| Weight | 0.035 kg |
|---|---|
| Suggested Use | Take 1 capsule, as needed, just prior to consuming high histamine foods or drinks. Or, take away from food if wanting to support healthy histamine levels in the digestive tract. Use as directed by your healthcare professional. Do not take this supplement and knowingly eat foods you are allergic to – it will not prevent allergic reactions. |
| Warnings | Children and pregnant or lactating women should consult their healthcare practitioner prior to use. This product contains an ingredient derived from porcine (pig). Avoid if allergic to pork or any other ingredient. Histamine Block is NOT EFFECTIVE for symptoms of immune-related food allergies, such as peanuts, shellfish, etc., or for gluten intolerance due to sensitivity or celiac disease. DAO is not absorbed and does not have systemic activity. Histamine Block does not manage or address antibody-related or IgE-related food allergies. |
Brand
Seeking Health
Seeking Health Australia
Practitioner-grade supplements designed for clarity, tolerance, and individual needs Seeking Health is a practitioner-focused supplement brand developed to support individual nutritional needs with a strong emphasis on formulation clarity and tolerance. Founded by Dr Ben Lynch, Seeking Health is best known for its work in areas such as methylation, histamine balance, gut health, and immune support. The brand offers a broad range of supplements — from everyday nutritional foundations to more targeted products for people who don’t respond well to standard formulations. At Fairfield, we stock a wide selection of Seeking Health products used by practitioners and individuals who want more control and predictability in how supplements affect them.What makes Seeking Health different
Designed for people who don’t tolerate “standard” supplements well
Many supplements are formulated with the assumption that everyone responds the same way. In practice, this often isn’t true. Seeking Health products are commonly chosen by people who:- feel overstimulated by certain vitamins (especially B vitamins)
- react poorly to additives or excipients
- need more flexibility around dose and form
- want supplements that can be adjusted rather than “one-size-fits-all”
How to think about using Seeking Health products
The range naturally divides neatly into the categories we like to use:- foundational products that suit many people and can be used long-term
- targeted products designed for specific patterns, sensitivities, or short-term support
🟢 Foundational Seeking Health products
Suitable for many people, including longer-term use Foundational products are typically used to support:- baseline nutrient intake
- nervous system and muscle function
- digestion and fat absorption
- general immune and metabolic health
- Optimal Multivitamin – comprehensive daily nutrient support with careful balance
- Multivitamin One – simplified daily multivitamin for those wanting fewer ingredients
- Optimal Magnesium – well-tolerated magnesium support for muscles and nervous system
- Vitamin C Plus – foundational antioxidant and immune support
- Vitamin D3 – baseline vitamin D support when sun exposure is limited
- Vitamin D3 + K2 – combined fat-soluble vitamin support for bone and cardiovascular health
- Fish Oil – omega-3 fatty acids for general inflammatory balance
- Digestive Enzymes – broad-spectrum enzyme support to assist digestion
- Optimal Man – foundational nutrient support formulated for male health needs
🟡 Targeted Seeking Health products
Best used for specific sensitivities or clearer needs A large part of the Seeking Health range is designed for more specific situations, particularly where standard supplements haven’t worked well. Targeted products are commonly used to support areas such as:- histamine sensitivity or intolerance
- methylation-related nutrient needs
- immune regulation
- gut-related reactivity
- stress and neurotransmitter balance
- added on top of foundations
- used with clearer intent
- reassessed rather than taken indefinitely
A practical note on individual response
Seeking Health products are intentionally flexible — which means responses can vary. Some people notice benefits quickly. Others may need to:- adjust dose
- simplify what they’re taking
- allow more time between introducing products
Why buy Seeking Health from Fairfield
- Australian-based, stocked locally — dispatched from Melbourne
- Fast shipping on in-stock items (same-day dispatch when ordered before 2pm)
- Wide Seeking Health range available in Australia
- Clear, conservative guidance — we prioritise understanding over upselling
Seeking Health products available at Fairfield
Browse the Seeking Health products we stock below. If you’re new to the brand, many people begin with foundational support before exploring more targeted options as needed.
