What is CoreBiotic Sensitive and who is it for?

CoreBiotic Sensitive is a spore-based probiotic supplement combining three fully sequenced and registered Bacillus strains: Bacillus coagulans SNZ1969, Bacillus coagulans MTCC 5856, and Bacillus subtilis DE111. This formula provides 11 billion CFU per serving without any prebiotic fibers.

Understanding that many of my clients follow low FODMAP diets or have sensitivities to fermentable fibers, having a high-quality spore-based option without prebiotics is essential. This is practitioner-grade quality delivered directly to you with the same care I’d provide in a clinical setting.

This product was specifically developed for individuals who need to avoid prebiotic fibers, including those following a low FODMAP diet, people with fiber sensitivities, or anyone working to support their gut health while minimizing fermentable carbohydrates. If you experience digestive sensitivity to standard probiotics containing inulin, FOS, or other prebiotic fibers, this formulation offers probiotic support without those ingredients.

Why choose spore-based probiotics?

Most standard probiotics contain Lactobacillus or Bifidobacterium strains that are sensitive to stomach acid, heat, and moisture. Many don’t survive the journey through your digestive tract. Spore-based probiotics are fundamentally different – they’re protected by a natural spore coating that allows them to remain dormant and stable until they reach the ideal environment in your gut.

How does it work?

Think of spore-based probiotics as seeds with a protective shell. The spore coating shields the probiotic bacteria as they pass through the acidic environment of your stomach, ensuring they arrive intact in your intestines where they can germinate, colonize, and provide their beneficial effects.

Survival advantage: Unlike fragile probiotic strains that require refrigeration and may lose potency during shipping and storage, spore-forming bacteria are remarkably resilient. They survive at room temperature, resist stomach acid, and have significantly higher colonization rates in the lower GI tract.

Targeted delivery: Once the spores reach the small and large intestines, they sense the favorable environment and germinate into active bacteria. These active cells support your existing microbiome by encouraging microbial diversity and supporting the populations of beneficial bacteria already present in your gut.

Strain-specific benefits: Each of the three Bacillus strains in CoreBiotic Sensitive has been fully sequenced and registered, ensuring you receive the same specific strains with each dose. Bacillus subtilis DE111 has achieved GRAS (Generally Recognized As Safe) status from the FDA and has been studied for its role in supporting digestive regularity. The two Bacillus coagulans strains are lactic acid-producing bacteria that support healthy gut pH.

What can this support?

This formula provides nutritional support for:

Following restrictive diets: When you’re on a low FODMAP diet or avoiding fermentable fibers, you still need probiotic support for your gut microbiome. This prebiotic-free formula fits within these dietary restrictions.

During or after antibiotic use: Antibiotics can disrupt your gut flora. Spore-based probiotics are particularly useful during this time because they’re not susceptible to antibiotic damage and can help support microbiome recovery.

Digestive sensitivity: If you’ve tried standard probiotics with prebiotics and experienced increased gas or bloating, this formula removes that variable while still providing the benefits of probiotic supplementation.

Travel support: The shelf-stable nature of spore probiotics makes them ideal for travel, maintaining their potency without refrigeration even in challenging conditions.

General microbiome maintenance: Supporting the diversity and health of your gut microbiome is an ongoing process. Regular probiotic supplementation can contribute to maintaining a healthy gut environment.

Common questions

How is this different from CoreBiotic original formula?
CoreBiotic Sensitive contains the same three Bacillus strains and the same 11 billion CFU potency as the original CoreBiotic, but without the VitaFiber™ prebiotic. This makes it suitable for individuals who need to avoid fiber-based prebiotics.

Does CoreBiotic Sensitive need to be refrigerated?
No. The spore-based nature of these probiotic strains means they remain stable at room temperature and do not require refrigeration.

Can I take this with other supplements?
Yes, spore-based probiotics can generally be taken alongside other supplements. However, if you’re taking antibiotics, separate the timing by at least 2-3 hours. Consult your healthcare practitioner if you have specific concerns about your supplement regimen.

What does “fully sequenced” mean and why does it matter?
Genomic sequencing verifies the exact genetic makeup of each bacterial strain. This ensures you’re getting the specific strains that have been researched and that the product maintains consistent strain specificity, potency, and safety batch after batch.

Is this safe for long-term use?
Spore-based probiotics like those in CoreBiotic Sensitive have been used safely in long-term studies. The DE111 strain has GRAS status, confirming its safety for ongoing consumption. As with any supplement regimen, work with your healthcare practitioner to determine what’s appropriate for your individual needs.

Key Features

• Three fully sequenced and registered spore-based Bacillus strains
• 11 billion CFU per serving
• Prebiotic-free formulation for sensitive individuals
• Compatible with low FODMAP diets
• No refrigeration required – shelf-stable
• Survives stomach acid for effective lower GI delivery
• Vegan and GMO-free
• Free from gluten, dairy, soy, and major allergens

Quality & Manufacturing

Researched Nutritionals is committed to practitioner-grade quality standards. CoreBiotic Sensitive is manufactured without milk, eggs, fish, crustacean shellfish, peanuts, wheat, and soy. The strains are genomically identified and registered, ensuring consistent quality and efficacy with every batch.

Suggested Use

Take 2 capsules once daily or as directed by your healthcare professional. Can be taken with or without food.

Ingredients (per 2 capsules)

• Bacillus coagulans SNZ1969 – spore-forming strain
• Bacillus coagulans MTCC 5856 – spore-forming strain
• Bacillus subtilis DE111® – spore-forming strain

Total CFU: 11 billion per serving
Other ingredients: Capsule shell (hypromellose, water), low moisture rice dextrin, medium chain triglycerides
Contains: Tree nuts (coconut – from MCT oil)
Free from: Gluten, dairy, soy, eggs, fish, shellfish, peanuts, wheat

These statements have not been evaluated by the TGA. This product is not intended to diagnose, treat, cure, or prevent any disease.