Triple Probiotic Bundle
Original price was: $180.40.$171.20Current price is: $171.20.
Probiotic bundle combining three distinct probiotic categories: spore-forming bacteria (MegaSporeBiotic), probiotic yeast (Saccharomyces boulardii), and strain-specific L. reuteri (BioGaia Gastrus).
This is our own clinically curated combination, designed to target the gut microbiome through the action of three different but complimentary types of probiotics.
Learn More about Triple Probiotic Therapy Here.
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What is the Triple Probiotic Bundle and who is it for?
The Triple Probiotic Bundle combines three practitioner-grade probiotics that work through completely different biological mechanisms: Microbiome Labs MegaSporeBiotic (spore-based bacteria), Yomogi Saccharomyces boulardii (probiotic yeast), and BioGaia Gastrus Pure Action (strain-specific L. reuteri). Because each product targets a different part of the gut ecosystem, they don’t compete with each other, they work together.
This bundle makes sense if you want the most comprehensive and flexible approach to supporting your gut microbiome through probiotics.
Read more about Triple Probiotic Therapy here.
Fairfield Nutrition Thoughts
Most people approach probiotics by looking for the highest CFU count or the longest list of strains, assuming more equals better. In practice, many multi-strain products contain dozens of bacteria working through essentially the same mechanism—they compete with each other for resources and may not even survive transit through stomach acid. This bundle takes a different approach: three genuinely distinct probiotic categories, each addressing a different layer of gut ecosystem support.
The combination of spore-based strains (which recondition the microbial environment), probiotic yeast (which competes with unwanted organisms and supports mucosal immunity), and strain-specific L. reuteri (with targeted upper GI research) covers significantly more ground than any single product can. Practitioners sometimes call this triple probiotic therapy—not because three is a magic number, but because these three mechanisms don’t overlap and work together. I use this combination regularly with clients because each product brings something genuinely different to the table, and together they address gut wellness from multiple angles.
Why This Formulation / How It Works
Why three separate probiotics instead of one?
Most probiotic supplements combine dozens of bacterial strains at high CFU counts and present this as comprehensive support. In practice, many of those strains work through similar mechanisms, compete with each other for the same resources, and may not survive stomach acid to reach the lower GI tract. This bundle takes a different approach: each product represents a fundamentally different category of probiotic organism—a spore-forming bacterium, a yeast, and a targeted bacterial strain with specific clinical research. Three products, three mechanisms, zero overlap.
All three products are shelf stable and require no refrigeration. MegaSporeBiotic’s spore-forming strains are inherently stable. Yomogi S. boulardii is a hardy yeast that survives room temperature storage. BioGaia Gastrus Pure Action uses a specialized encapsulation process that protects the L. reuteri strains without requiring cold storage.
Three layers of gut ecosystem support
Think of your gut ecosystem like a garden. You wouldn’t just scatter one type of seed and hope for the best—you’d prepare the soil, protect against pests, and plant specific species where they’re suited to grow. This bundle works on the same principle, addressing three distinct layers of gut wellness support.
Microbiome reconditioning with spore-based strains
The five Bacillus spore strains in MegaSporeBiotic form protective endospores that survive stomach acid and germinate in the lower GI tract. Rather than trying to implant specific bacteria, they support conditions in which your own diverse, beneficial species can establish themselves. Bacillus spores produce compounds that influence the local microbial environment and gut barrier tissue. Research on these specific strains shows they support gut barrier integrity and microbial diversity—two foundational aspects of digestive wellness.
Pathogen competition and mucosal immune support with probiotic yeast
Saccharomyces boulardii is a probiotic yeast, not a bacterium, and this distinction matters. It competes with unwanted organisms through physical crowding in the intestinal lining, produces substances that help neutralize certain bacterial toxins, and supports the local mucosal immune response. Because it’s a yeast, it’s unaffected by antibiotics and doesn’t compete with the bacterial probiotics in this bundle—it occupies a completely different ecological niche.
Strain-specific upper GI support with L. reuteri
BioGaia Gastrus Pure Action contains two specific, patented human-derived strains of Lactobacillus reuteri: DSM 17938 and ATCC PTA 6475. The clinical research on upper GI motility and immune modulation is tied to these exact strains, not to L. reuteri generically. These strains colonize the upper digestive tract and produce compounds that support normal gastric function and upper GI comfort. This is the same formulation popularized through Dr. William Davis’s work on L. reuteri and is vegan, FODMAP-friendly, and free from gluten, dairy, and artificial additives.
When to Consider This
This bundle provides nutritional support for gut microbiome wellness. It makes sense if you’re:
- Scenario 1: You’ve tried multiple standard multi-strain probiotics without noticing lasting changes and want to address gut wellness through fundamentally different mechanisms.
- Scenario 2: You’re taking or have recently completed a course of antibiotics and want to support your gut microbiome during recovery (S. boulardii is unaffected by antibiotics, and spore-based strains show greater resilience than standard lactobacillus strains).
- Scenario 3: You’re working with a practitioner on gut barrier integrity or comprehensive digestive wellness protocols and want a systematic, multi-mechanism approach rather than guessing at which single probiotic might work.
Supplement strategy: Many people introduce this bundle after establishing dietary foundations for gut wellness. Practitioners commonly use this combination for 8-12 weeks to support meaningful shifts in microbial diversity, though S. boulardii and L. reuteri can be used on an ongoing basis. Often used alongside prebiotic fibers or other gut-supportive nutrients as part of a broader microbiome protocol.
⚠️ Not suitable for: People with compromised immune systems or central venous catheters should consult their healthcare practitioner before using S. boulardii. If you are pregnant, breastfeeding, or taking medication, consult your healthcare practitioner before use.
How to Use
MegaSporeBiotic: Take 2 capsules daily with a meal. If new to spore-based probiotics, start with 1 capsule daily for the first week, then increase to 2 capsules daily. Each capsule provides 4 billion CFU of five Bacillus spore-forming strains.
Yomogi S. boulardii: Take 1 capsule daily, with or without food. Each capsule provides 250mg S. boulardii.
BioGaia Gastrus Pure Action: Take 1 capsule daily, with or without food. Each capsule provides 200 million CFU of two patented L. reuteri strains (DSM 17938 and ATCC PTA 6475).
You can take all three products at the same time or spread them throughout the day—the mechanisms don’t interfere with each other. Most practitioners recommend a minimum of 8-12 weeks to allow the spore-based strains to support meaningful shifts in microbial diversity.
Ingredients
What’s included in this bundle:
Microbiome Labs MegaSporeBiotic (60 capsules)
Per 2 capsules: 4 billion CFU
Bacillus indicus HU36
Bacillus subtilis HU58
Bacillus coagulans
Bacillus licheniformis
Bacillus clausii
Other ingredients: Cellulose, vegetable capsule
Yomogi Saccharomyces boulardii (30 capsules)
Per capsule: 250mg Saccharomyces boulardii
Other ingredients: Cellulose, vegetable capsule
BioGaia Gastrus Pure Action (60 capsules)
Per capsule: 200 million CFU
Lactobacillus reuteri DSM 17938
Lactobacillus reuteri ATCC PTA 6475
Other ingredients: Sunflower oil, medium chain triglycerides, vegetable capsule
Allergen information: BioGaia Gastrus Pure Action is vegan, FODMAP-friendly, and free from gluten, dairy, soy, and artificial additives. MegaSporeBiotic and Yomogi are free from common allergens.
Common Questions
Should I start by taking just all 3 probiotics at the same time or one by one?
This depends on the individual and how sensitive they are. For further guidance, see our more detailed article on triple probiotic therapy.
Do I need to take all three at the same time of day?
No. MegaSporeBiotic is best taken with a meal. Yomogi and BioGaia Gastrus can be taken with or without food. You can spread them through the day or take them together—the mechanisms don’t interfere with each other.
Can I take this bundle alongside other supplements?
Yes. Because each product works through independent mechanisms, they’re compatible with most other supplement protocols. If you’re taking MegaPreBiotic or other Microbiome Labs products, MegaSporeBiotic is designed to work alongside them.
Is this suitable during antibiotic treatment?
S. boulardii (Yomogi) is unaffected by antibiotics and can be taken during a course. MegaSporeBiotic’s spore-forming strains also show greater resilience than standard probiotics. BioGaia Gastrus can be taken as usual. If in doubt, consult your prescribing practitioner.
How long should I take this bundle for?
Most practitioners recommend a minimum of 8-12 weeks to allow the spore-based strains to support meaningful shifts in microbial diversity. S. boulardii and L. reuteri can be used on an ongoing basis or for targeted periods. Follow your practitioner’s guidance for your situation.
Why not just buy a single probiotic with more strains and a higher CFU count?
CFU count measures quantity, not diversity of mechanism. A 100-billion-CFU product containing 20 strains of lactobacillus and bifidobacterium is still working through essentially one mechanism. This bundle provides three genuinely different types of probiotic organism—spore-based, yeast-based, and strain-specific bacteria—each targeting different aspects of gut wellness.
Is the bundle cheaper than buying individually?
Yes. The bundle is priced below the combined individual retail prices, making it the most cost-effective way to run all three products together.
Warnings & Storage
Do not use if: You have a compromised immune system or central venous catheter without consulting your healthcare practitioner. Pregnant or breastfeeding women should consult their healthcare practitioner before use.
Cautions: If you are taking medications or have pre-existing health conditions, consult your healthcare practitioner before use. Do not exceed the recommended dose.
Storage: All three products are shelf stable. Store in a cool, dry place away from direct sunlight. No refrigeration required.
Always consult your healthcare professional before use if you have any pre-existing conditions or are taking medications.
| Weight | 0.4 kg |
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Yomogi Saccharomyces cerevisiae (boulardii) Probiotic
| Size | 50 caps |
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BioGaia Gastrus Pure Action L-Reuteri Probiotic - 60 capsules
| Shipping and Returns | Standard delivery times of 1-7 business days are to be expected. Free express delivery for orders over $175. No questions asked returns and refund within 30 days. |
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Microbiome Labs MegaSporeBiotic
| Active Ingredient | Bacillus clausii, Bacillus coagulans, Bacillus indicus, Bacillus licheniformis, Bacillus subtilis, Spore Based Probiotics |
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| Size | 60 caps |
